DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Antp and HB-3

DIOPT Version :9

Sequence 1:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_568309.2	Gene:	HB-3 / 831367	AraportID:	AT5G15150	Length:	314	Species:	Arabidopsis thaliana

Alignment Length:	180	Identity:	47/180 - (26%)
Similarity:	68/180 - (37%)	Gaps:	46/180 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 MNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQN--HHNMGMYQQQSGVP-PVGAP--PQGMMHQ 250
            :..:|..|.|        |:.      ..::|::  ||          :| |...|  |..:.:.
plant    18 LRLEMAFPQH--------GFM------FQQLHEDNAHH----------LPSPTSLPSCPPHLFYG 58

  Fly   251 GQGPPQMHQG----------HPGQHTP-PSQNPNSQSS-GMPSPLYPWMRSQFGKCQERKRGRQT 303
            |.|...|::.          |..|.:| .:.|.|.|.. |....|     |..|........::.
plant    59 GGGNYMMNRSMSFTGVSDHHHLTQKSPTTTNNMNDQDQVGEEDNL-----SDDGSHMMLGEKKKR 118

  Fly   304 YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK 353
            ....|...|||.|.....|...|::::|.||.|..|||.|||||||.:||
plant   119 LNLEQVRALEKSFELGNKLEPERKMQLAKALGLQPRQIAIWFQNRRARWK 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	24/131 (18%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	23/53 (43%)
HB-3	NP_568309.2	HOX	115..168	CDD:197696	21/52 (40%)
HB-3	NP_568309.2	HALZ	170..208	CDD:280364
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4196
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910