Protein Alignment Antp and Cdx2

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_076453.1
• Gene: Cdx2 / 66019
• RGDID: 621234
• Length: 310
• Species: Rattus norvegicus
• Alignment Length: 261
• Identity: 78/261 - (29%)
• Similarity: 107/261 - (40%)
• Gaps: 74/261 - (28%)

  Fly   169 GGLGMVPEG-GSPPLVDQMSGHHM-----------NAQMTLP----------------------- 198
            |||.:.|:. .|||......|:|:           :||...|
  Rat    22 GGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQSPGPSWPTAYGAPLREDWNGYAPGGAA 86

  Fly   199 ------HHM--GHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVP------PVGAP--PQGM 247
                  |.:  |.|.|.:||:     ...|.|.:||           |      |..||  ..|:
  Rat    87 AANAVAHGLNGGSPAAAMGYS-----SPAEYHAHHH-----------PHHHPHHPAAAPSCASGL 135

  Fly   248 MHQ-GQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLE 311
            :.. ..|||........:...||....:....|..|..|.:.||. |.:.:.:.|..||.:|.||
  Rat   136 LQTLNPGPPGPAATAAAEQLSPSGQRRNLCEWMRKPAQPSLGSQV-KTRTKDKYRVVYTDHQRLE 199

  Fly   312 LEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGEGDEITPPNS 376
            ||||||::||:|.||:.|:|..|.|:|||:||||||||.|.:|.||.|.:     :..:..||..
  Rat   200 LEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKLQ-----QQQQQQPPAP 259

  Fly   377 P 377
            |
  Rat   260 P 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	40/188 (21%)
		Homeodomain	298..354	CDD:459649	33/55 (60%)
Cdx2	NP_076453.1	Caudal_act	13..178	CDD:461413	35/171 (20%)
		Homeodomain	187..242	CDD:459649	33/54 (61%)