DRSC/TRiP Functional Genomics Resources

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Protein Alignment Antp and POU3F1

DIOPT Version :9

Sequence 1:NP_996167.1 Gene:Antp / 40835 FlyBaseID:FBgn0260642 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_002690.3 Gene:POU3F1 / 5453 HGNCID:9214 Length:451 Species:Homo sapiens


Alignment Length:349 Identity:67/349 - (19%)
Similarity:99/349 - (28%) Gaps:144/349 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   165 QAAVGGLGMVPEGGS-----PPLVDQMSGH--HMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVH 222
            :|..||.|...:||.     ..||.|.:.|  ...||.:..||:|...:.       .|..:..|
Human    94 KAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSP-------SPGASGGH 151

  Fly   223 QNHHNMGMYQQQSGVPPVGAPPQGMMHQGQG--PPQMH-----QGHPGQ---HTPPSQNPNSQSS 277
            | ...:|:|.|.:.....|....||:..|.|  .|.:|     .||..|   ..||....:..:.
Human   152 Q-PQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAH 215

  Fly   278 G---------MPSPLYPWM--------------------RSQFGKCQERKR-------------- 299
            |         ..:.|:|..                    ..||.|..:::|              
Human   216 GHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLAL 280

  Fly   300 --------GRQTYTRYQTLE-----------------------------LEKEFHFNRYLTRRRR 327
                    .:.|..|::.|:                             |:|.....|...:|..
Human   281 GTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTS 345

  Fly   328 IEI------------------------AHALCLTERQIKIWFQNRRMKWKKENKTKGE------- 361
            ||:                        |.:|.|.:..:::||.|||.|.|:.....|.       
Human   346 IEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDD 410

  Fly   362 --------PGSGGEGDEITPPNSP 377
                    ||.||......||..|
Human   411 VYAPGELGPGGGGASPPSAPPPPP 434

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AntpNP_996167.1 KLF1_2_4_N <161..306 CDD:425360 41/208 (20%)
Homeobox 301..354 CDD:395001 18/105 (17%)
POU3F1NP_002690.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 69..114 6/19 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 127..154 8/34 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 186..253 9/66 (14%)
POU 247..321 CDD:197673 7/73 (10%)
Homeobox 342..396 CDD:395001 12/53 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 395..451 9/40 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3844
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.030

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