DRSC/TRiP Functional Genomics Resources

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Protein Alignment Antp and PITX2

DIOPT Version :10

Sequence 1:NP_996167.1 Gene:Antp / 40835 FlyBaseID:FBgn0260642 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_000316.2 Gene:PITX2 / 5308 HGNCID:9005 Length:324 Species:Homo sapiens


Alignment Length:103 Identity:35/103 - (33%)
Similarity:49/103 - (47%) Gaps:10/103 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   269 SQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHA 333
            ||...::..|...|         .|.:.::|.|..:|..|..|||..|..|||.....|.|||..
Human    73 SQQGKNEDVGAEDP---------SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVW 128

  Fly   334 LCLTERQIKIWFQNRRMKW-KKENKTKGEPGSGGEGDE 370
            ..|||.::::||:|||.|| |:|...:.|....|.|.:
Human   129 TNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQ 166

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AntpNP_996167.1 KLF1_2_4_N <161..306 CDD:425360 7/36 (19%)
Homeodomain 298..354 CDD:459649 25/56 (45%)
PITX2NP_000316.2 Homeodomain 93..149 CDD:459649 25/55 (45%)
OAR 282..299 CDD:461067
Blue background indicates that the domain is not in the aligned region.

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