Protein Alignment Antp and PRRX2

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_057391.1
• Gene: PRRX2 / 51450
• HGNCID: 21338
• Length: 253
• Species: Homo sapiens
• Alignment Length: 161
• Identity: 39/161 - (24%)
• Similarity: 61/161 - (37%)
• Gaps: 53/161 - (32%)

  Fly   236 GVPPVGAPPQGMMHQGQGPPQMHQ-----------------------GHPGQHTP----PSQNPN 273
            |.||   ||..:     ||....|                       ..||....    .::.|:
Human    18 GPPP---PPPAL-----GPGDCAQARKNFSVSHLLDLEEVAAAGRLAARPGARAEAREGAAREPS 74

  Fly   274 SQSSGMPSPLYPWMRSQFGKC------------QERKRGRQTYTRYQTLELEKEFHFNRYLTRRR 326
            ..|||  |...|    |.|:|            ::::|.|.|:...|...||:.|....|.....
Human    75 GGSSG--SEAAP----QDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFV 133

  Fly   327 RIEIAHALCLTERQIKIWFQNRRMKWKKENK 357
            |.|:|..:.|:|.::::||||||.|:::..:
Human   134 REELARRVNLSEARVQVWFQNRRAKFRRNER 164

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	22/108 (20%)
		Homeodomain	298..354	CDD:459649	20/55 (36%)
PRRX2	NP_057391.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33		7/22 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	55..113		14/63 (22%)
		Homeodomain	109..161	CDD:459649	18/51 (35%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	230..243