Protein Alignment Antp and NKX2-2

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_002500.1
• Gene: NKX2-2 / 4821
• HGNCID: 7835
• Length: 273
• Species: Homo sapiens
• Alignment Length: 186
• Identity: 49/186 - (26%)
• Similarity: 73/186 - (39%)
• Gaps: 58/186 - (31%)

  Fly   241 GAPPQGMMHQGQGP-PQMHQGHPGQ------HTPPSQNPNSQSSGMPSPLYPWMRS----QF--- 291
            |:..:|...:.:|| |....|..||      .:.|.:||...||  .:|...|:.|    |:
Human    26 GSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLPLKNPFYDSS--DNPYTRWLASTEGLQYSLH 88

  Fly   292 ----------------------------------GKCQERKRGRQTYTRYQTLELEKEFHFNRYL 322
                                              |...::::.|..:::.||.|||:.|...|||
Human    89 GLAAGAPPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYL 153

  Fly   323 TRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGEGDEITPPNSPQ 378
            :...|..:|..:.||..|:||||||.|.|.|:....||.        |:||..||:
Human   154 SAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGM--------EVTPLPSPR 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	19/112 (17%)
		Homeodomain	298..354	CDD:459649	23/55 (42%)
NKX2-2	NP_002500.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		8/29 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..131		1/40 (3%)
		Homeodomain	129..185	CDD:459649	23/55 (42%)