Protein Alignment Antp and MSX1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_002439.2
• Gene: MSX1 / 4487
• HGNCID: 7391
• Length: 303
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 61/229 - (26%)
• Similarity: 85/229 - (37%)
• Gaps: 65/229 - (28%)

  Fly   167 AVGGLGMVP--------------EGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPD 217
            |.||.|..|              ||..|.:...:....:.|.|......|..::.|..:: ||
Human    25 AGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAPSE-GV-- 86

  Fly   218 VTEVHQNHHNMGMYQQQSGVPP--VGAP--------------------PQGMMHQGQGPPQMHQG 260
                    ...|...|..||||  :|||                    |:..:.:.:.|.:
Human    87 --------QAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEK---- 139

  Fly   261 HPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERK-----RGRQTYTRYQTLELEKEFHFNR 320
                   |.:.|..||.....|  |..|.....|..||     :.|..:|..|.|.||::|...:
Human   140 -------PERTPWMQSPRFSPP--PARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQ 195

  Fly   321 YLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 354
            ||:...|.|.:.:|.|||.|:||||||||.|.|:
Human   196 YLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKR 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	36/179 (20%)
		Homeodomain	298..354	CDD:459649	26/60 (43%)
MSX1	NP_002439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..55		8/29 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..117		13/58 (22%)
		PTZ00449	<105..>248	CDD:185628	40/138 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..174		11/53 (21%)
		Homeodomain	173..229	CDD:459649	25/55 (45%)