Protein Alignment Antp and cdx1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_989416.1
• Gene: cdx1 / 395055
• XenbaseID: XB-GENE-485396
• Length: 262
• Species: Xenopus tropicalis
• Alignment Length: 227
• Identity: 82/227 - (36%)
• Similarity: 104/227 - (45%)
• Gaps: 40/227 - (17%)

  Fly   170 GLGMVPEG---GSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMY 231
            ||.:.|:.   ..|...|..|.||:....:.||| |.|.....       ..|...::.|..|
 Frog    22 GLNLNPQNYVPAPPQYSDFPSYHHVPGINSDPHH-GQPGGTWS-------SYTPSREDWHPYG-- 76

  Fly   232 QQQSGVPPVGA----PPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSP----LYPWMR 288
                  |..||    |.|.........|....| ||. .|||.| :|.|...||.    ||.|||
 Frog    77 ------PGPGASSANPAQISFSPSDYNPVQPPG-PGL-LPPSLN-SSVSPLSPSAQRRNLYEWMR 132

  Fly   289 --------SQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWF 345
                    :..||.:.:.:.|..||.:|.||||||||::||:|.||:.|:|.:|.|||||:||||
 Frog   133 RTGVPTSTNSNGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAASLALTERQVKIWF 197

  Fly   346 QNRRMKWKKENKTKGEPGSGGEGDEITPPNSP 377
            ||||.|.:|.||.|.:..|  :....|.|..|
 Frog   198 QNRRAKERKVNKKKMQQQS--QQASTTTPTPP 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	42/154 (27%)
		Homeodomain	298..354	CDD:459649	34/55 (62%)
cdx1	NP_989416.1	Caudal_act	13..141	CDD:461413	38/137 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..120		26/96 (27%)
		Homeodomain	151..206	CDD:459649	34/54 (63%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	152..173		12/20 (60%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	191..202		9/10 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..262		9/27 (33%)