Protein Alignment Antp and en

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 102/520 - (19%)
• Similarity: 137/520 - (26%)
• Gaps: 259/520 - (49%)

  Fly    88 SPSSQVGGVMPQAQTNGQLGVPQQQQQQQQQPSQNQQQQQAQQAPQQLQQQLPQVTQQVTHP--- 149
            ||.|....:..|.|     .:..||||||||..|.|...|.||..|..||||  ......||
  Fly     8 SPQSAPSPITLQMQ-----HLHHQQQQQQQQQQQMQHLHQLQQLQQLHQQQL--AAGVFHHPAMA 65

  Fly   150 -----------------------QQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLVDQMSGHHM 191
                                   ||:.......|||...|:...| .:.|..|..::..||.|:.
  Fly    66 FDAAAAAAAAAAAAAAHAHAAALQQRLSGSGSPASCSTPASSTPL-TIKEEESDSVIGDMSFHNQ 129

  Fly   192 -------------------------NAQMTLPHHMGHPQAQ--LGYT----------DVGVP--- 216
                                     ..::..|.|.....|:  |.::          ||..|
  Fly   130 THTTNEEEEAEEDDDIDVDVDDTSAGGRLPPPAHQQQSTAKPSLAFSISNILSDRFGDVQKPGKS 194

  Fly   217 ---------------------------DVTEVHQ---------------------NHHNMGMYQQ 233
                                       |:.|..:                     |..|...|.:
  Fly   195 MENQASIFRPFEASRSQTATPSAFTRVDLLEFSRQQQAAAAAATAAMMLERANFLNCFNPAAYPR 259

  Fly   234 ---------------QSGVPP-------------------------VGAPPQGMMHQGQGPPQMH 258
                           .:.:||                         :|.|....|.|   ||...
  Fly   260 IHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQ---PPLSS 321

  Fly   259 QGHPGQHTPPSQN-------------------------------PNSQ----------SSGMPSP 282
            ........||:.|                               |:|:          ||..|.|
  Fly   322 SASSLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQP 386

  Fly   283 LYP-----------------------------------WM-------RSQFG-----------KC 294
            :.|                                   |:       |...|           |.
  Fly   387 IPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKT 451

  Fly   295 QERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTK 359
            .:.||.|..::..|...|::||:.|||||.|||.:::..|.|.|.||||||||:|.|.||...:|
  Fly   452 NDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSK 516

  Fly   360  359
              Fly   517  516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	46/366 (13%)
		Homeodomain	298..354	CDD:459649	28/55 (51%)
en	NP_523700.2	Homeodomain	455..511	CDD:459649	28/55 (51%)
		Engrail_1_C_sig	512..542	CDD:431338	1/5 (20%)