DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Antp and pnx

DIOPT Version :9

Sequence 1:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_840087.1	Gene:	pnx / 352939	ZFINID:	ZDB-GENE-030328-42	Length:	182	Species:	Danio rerio

Alignment Length:	111	Identity:	41/111 - (36%)
Similarity:	54/111 - (48%)	Gaps:	15/111 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 TPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEI 330
            |.|:|.|::          |.:.:......:.||.|..:|..|...||:.|..:.||:...|..|
Zfish    46 TSPTQEPSA----------PNIANASAAKVKSKRIRTAFTLDQLRILERSFQSSHYLSVFERHCI 100

  Fly   331 AHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGEGDEITPPNS 376
            |.||.|:|.|:||||||||.|||||     ..|.|||......|.:
Zfish   101 ASALGLSETQVKIWFQNRRTKWKKE-----LDGHGGEEQSHCAPTA 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	8/39 (21%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	26/52 (50%)
pnx	NP_840087.1	Important for interaction with tle3a. /evidence=ECO:0000269\|PubMed:12642490	1..34
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	24..63		5/26 (19%)
		Homeobox	71..123	CDD:278475	25/51 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810