Protein Alignment Antp and HOXD11

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_067015.2
• Gene: HOXD11 / 3237
• HGNCID: 5134
• Length: 338
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 85/363 - (23%)
• Similarity: 122/363 - (33%)
• Gaps: 108/363 - (29%)

  Fly    46 SQNANHQGNMPY-----PRFPPY------------DRMPYYNGQGMDQQQQHQVYSRPDSPSSQV 93
            ||.::.|...||     |...|.            .:.||..|.|............|.......
Human    36 SQPSSCQMTFPYSSNLAPHVQPVREVAFRDYGLERAKWPYRGGGGGGSAGGGSSGGGPGGGGGGA 100

  Fly    94 GGVMP-----QAQTNGQLGVPQQQQQQQQQPSQNQQQQQAQQAPQQLQQQLPQVTQQVTHPQQQQ 153
            ||..|     .|.........:...|::..|...::.....:||
Human   101 GGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPAGRRPDVLFKAP--------------------- 144

  Fly   154 QQPV----------VYASCKLQAAVGGLGMVPEG--------GSPPLVDQMSGHHMNAQMTLPHH 200
             :||          ..|:....:|||..|::|:|        ..||......          |..
Human   145 -EPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQP----------PPP 198

  Fly   201 MGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQ- 264
            ...||.: |..|.|.|                 ::|....|..|......|..|....:|..|.
Human   199 PAPPQPE-GAADKGDP-----------------RTGAGGGGGSPCTKATPGSEPKGAAEGSGGDG 245

  Fly   265 HTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIE 329
            ..||.:....:||...:|            |..::.|..||:||..|||:||.||.|:.:.:|::
Human   246 EGPPGEAGAEKSSSAVAP------------QRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQ 298

  Fly   330 IAHALCLTERQIKIWFQNRRMKWKKENKTK-----GEP 362
            ::..|.||:||:||||||||||.||.|:.:     |.|
Human   299 LSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNP 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	30/153 (20%)
		Homeodomain	298..354	CDD:459649	29/55 (53%)
HOXD11	NP_067015.2	DUF3528	26..185	CDD:432284	29/170 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..270		22/130 (17%)
		Homeodomain	267..323	CDD:459649	29/55 (53%)