Protein Alignment Antp and HOXD8

DIOPT Version :9

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_062458.1
• Gene: HOXD8 / 3234
• HGNCID: 5139
• Length: 290
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 93/277 - (33%)
• Similarity: 113/277 - (40%)
• Gaps: 93/277 - (33%)

  Fly   163 KLQAAVGGLGMVPEGGSPPLVD-----QMSGHHMNAQMTLPHHMGHPQAQL-GYTDVGVPDV-TE 220
            |.:||........|..:|...|     ::.|.|..|...|         || |.:..|.|.. .:
Human    12 KYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAAL---------QLYGNSAAGFPHAPPQ 67

  Fly   221 VHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQG----------------HPGQHTPPS 269
            .|.:.|        ...||.|....|  .:|:|....|.|                ||....||.
Human    68 AHAHPH--------PSPPPSGTGCGG--REGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPPPP 122

  Fly   270 -----------------------------------QNPNSQS--------------SGMPSPLYP 285
                                               |.|:.:|              |..||.::|
Human   123 PCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFP 187

  Fly   286 WMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRM 350
            |||.|  ....|:||||||:|:|||||||||.||.||||:||||::|||.|||||:|||||||||
Human   188 WMRPQ--AAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRM 250

  Fly   351 KWKKENKTKGEPGSGGE 367
            ||||||.....|.|..|
Human   251 KWKKENNKDKFPVSRQE 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	47/214 (22%)
		Homeobox	301..354	CDD:395001	43/52 (83%)
HOXD8	NP_062458.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..127		16/76 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..200		10/40 (25%)
		Homeobox	201..253	CDD:278475	42/51 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..290		5/13 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.810