Protein Alignment Antp and HOXD4

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 87/237 - (36%)
• Similarity: 106/237 - (44%)
• Gaps: 56/237 - (23%)

  Fly   180 PPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQ---------S 235
            ||..:.:.|.::..| ...::.|..|.    .|...|            |:|.:.         |
Human    18 PPCEEYLQGGYLGEQ-GADYYGGGAQG----ADFQPP------------GLYPRPDFGEQPFGGS 65

  Fly   236 GVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTP--------------------PSQNPNSQSSGMP 280
            |..|..|.|.....|..|.|..|...||:..|                    |.|.|:..:...|
Human    66 GPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQPPSGTALKQP 130

  Fly   281 SPLYPWMRSQFGKC-------QERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTE 338
            :.:||||:......       .|.||.|..|||.|.|||||||||||||||||||||||.|||:|
Human   131 AVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSE 195

  Fly   339 RQIKIWFQNRRMKWKKENK---TKGEPGSGGEGDEITPPNSP 377
            ||||||||||||||||::|   |||...|.......:...:|
Human   196 RQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAP 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	35/161 (22%)
		Homeodomain	298..354	CDD:459649	48/55 (87%)
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		22/112 (20%)
		Antp-type hexapeptide	133..138		3/4 (75%)
		Homeodomain	155..211	CDD:459649	48/55 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		6/26 (23%)