Protein Alignment Antp and HOXC10

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_059105.2
• Gene: HOXC10 / 3226
• HGNCID: 5122
• Length: 342
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 77/273 - (28%)
• Similarity: 115/273 - (42%)
• Gaps: 72/273 - (26%)

  Fly   130 QAPQQLQQQLPQVTQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPEGG--SPPLVDQMSGHH-- 190
            :|..:|:|.:.:.....::|...:::.|    |.:.:|.......||..  |.||.:...|.|
Human    83 KAAYRLEQPVGRPLSSCSYPPSVKEENV----CCMYSAEKRAKSGPEAALYSHPLPESCLGEHEV 143

  Fly   191 -----------MNAQMTLPHHMG--------------HPQA------QLG---------YTDVGV 215
                       .:|....||..|              :|:|      |||         .:|...
Human   144 PVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDSQT 208

  Fly   216 PDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTP-PSQNPNSQSSGM 279
            |...|:.         .:||...|.|:|.:.         :..:......:| .|.|...:....
Human   209 PSPNEIK---------TEQSLAGPKGSPSES---------EKERAKAADSSPDTSDNEAKEEIKA 255

  Fly   280 PSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIW 344
            .:....|:.::.|    ||: |..||::|||||||||.||.||||.||:||:..:.||:||:|||
Human   256 ENTTGNWLTAKSG----RKK-RCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIW 315

  Fly   345 FQNRRMKWKKENK 357
            |||||||.||.|:
Human   316 FQNRRMKLKKMNR 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	35/189 (19%)
		Homeodomain	298..354	CDD:459649	37/55 (67%)
HOXC10	NP_059105.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..271		17/105 (16%)
		Homeodomain	269..325	CDD:459649	38/56 (68%)