Protein Alignment Antp and HOXB6

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 110/323 - (34%)
• Similarity: 147/323 - (45%)
• Gaps: 82/323 - (25%)

  Fly    86 PDSPSSQVGGVMPQAQTNGQLGVPQQQQQQQQQPSQNQQQQQAQQAPQQLQQQLPQVTQQVTHPQ 150
            |.||     |.:|:   |.|:    .:..::::|....:|.....|.::...:    |||:.:|.
Human     5 PPSP-----GSLPE---NAQV----SRHSRRREPRSTGRQFCGFNAARRSDYK----TQQIINPA 53

  Fly   151 QQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQ----AQLGYT 211
            :||:                    |.  :|||  .||.:.:|:  |.|..:...|    .||...
Human    54 EQQR--------------------PR--APPL--PMSSYFVNS--TFPVTLASGQESFLGQLPLY 92

  Fly   212 DVGVPDVTEVHQNHHNMGMYQQQ-----SGVPPVGAPPQGMMHQGQGP-PQMHQ----------- 259
            ..|..|....:...:..|..|.:     |..||.|...........|| |..::
Human    93 SSGYADPLRHYPAPYGPGPGQDKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGA 157

  Fly   260 -GHPGQHTPPSQNPNSQSSGM---------PSPLYPWMR-------SQFGKCQERKRGRQTYTRY 307
             ..|..|..|.::..:|...:         .:|:||||:       |.||  ...:|||||||||
Human   158 DEQPPFHPEPRKSDCAQDKSVFGETEEQKCSTPVYPWMQRMNSCNSSSFG--PSGRRGRQTYTRY 220

  Fly   308 QTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGEGDE 370
            ||||||||||:|||||||||||||||||||||||||||||||||||||:|.........|.:|
Human   221 QTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEE 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	41/182 (23%)
		Homeodomain	298..354	CDD:459649	53/55 (96%)
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	53/55 (96%)