Protein Alignment Antp and HOXB4

DIOPT Version :9

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_076920.1
• Gene: HOXB4 / 3214
• HGNCID: 5115
• Length: 251
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 90/234 - (38%)
• Similarity: 105/234 - (44%)
• Gaps: 67/234 - (28%)

  Fly   210 YTDVGVPDVTEVHQ-----NHHNMGMY----------QQQSGV---------------------- 237
            |.|...|...|..|     :.|:.|.|          |.::|.
Human    12 YVDPKFPPCEEYSQSDYLPSDHSPGYYAGGQRRESSFQPEAGFGRRAACTVQRYAACRDPGPPPP 76

  Fly   238 ---PPVGAPPQGMMHQGQGPPQMHQ--GHPGQH-----TPPSQNPNSQSSGMPSP---------L 283
               ||...||.|:..:...||....  ..|||.     :.|...|.:|:...|||         :
Human    77 PPPPPPPPPPPGLSPRAPAPPPAGALLPEPGQRCEAVSSSPPPPPCAQNPLHPSPSHSACKEPVV 141

  Fly   284 YPWMRSQFGKC-------QERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQI 341
            |||||......       .|.||.|..|||.|.||||||||:|||||||||:||||||||:||||
Human   142 YPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQI 206

  Fly   342 KIWFQNRRMKWKKENK---TKGEPGSGGEGDEITPPNSP 377
            |||||||||||||::|   ||...| |..|....||..|
Human   207 KIWFQNRRMKWKKDHKLPNTKIRSG-GAAGSAGGPPGRP 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	36/158 (23%)
		Homeobox	301..354	CDD:395001	45/52 (87%)
HOXB4	NP_076920.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..134		26/121 (21%)
		Antp-type hexapeptide	141..146		3/4 (75%)
		Homeobox	165..218	CDD:278475	44/52 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	220..251		9/26 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810