Protein Alignment Antp and HOXB2

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_002136.1
• Gene: HOXB2 / 3212
• HGNCID: 5113
• Length: 356
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 66/219 - (30%)
• Similarity: 88/219 - (40%)
• Gaps: 80/219 - (36%)

  Fly   216 PDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPS--QNPNSQS-- 276
            |.|.|..|.    ...::.:.:||              ||...|..|......|  |.|.||.
Human    26 PAVLETFQT----SSIKESTLIPP--------------PPPFEQTFPSLQPGASTLQRPRSQKRA 72

  Fly   277 ---------------SGMPSPLYPWMRSQFGKCQER----------------------------- 297
                           :..|:|.:|||:.:  |..::
Human    73 EDGPALPPPPPPPLPAAPPAPEFPWMKEK--KSAKKPSQSATSPSPAASAVPASGVGSPADGLGL 135

  Fly   298 --------KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 354
                    :|.|..||..|.||||||||||:||.|.||:|||..|.|||||:|:||||||||.|:
Human   136 PEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 200

  Fly   355 ENKTK----GEPGSGGEGDEITPP 374
            :.:.:    |||...|..::|..|
Human   201 QTQHREPPDGEPACPGALEDICDP 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	24/145 (17%)
		Homeodomain	298..354	CDD:459649	38/55 (69%)
HOXB2	NP_002136.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..142		17/118 (14%)
		Antp-type hexapeptide	94..99		2/4 (50%)
		Homeodomain	144..200	CDD:459649	38/55 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..240		8/28 (29%)