Protein Alignment Antp and HOXA11

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_005514.1
• Gene: HOXA11 / 3207
• HGNCID: 5101
• Length: 313
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 78/288 - (27%)
• Similarity: 113/288 - (39%)
• Gaps: 62/288 - (21%)

  Fly   119 PSQNQQQQQAQQAPQQLQQQLPQV--TQQVT------------HPQQQ-----QQQPVVYASCKL 164
            ||...|...::.........||||  .::||            ||:..     ..:.:|:..| |
Human    31 PSFLPQTPSSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRDC-L 94

  Fly   165 QA--AVGGLGMVPEGGSPPLVDQMSGHH------MNAQMTLPHHMGHPQA--QLGYTDVGVPDVT 219
            ||  |.|..|.|....|..:.     ||      .|...|:..:...|||  |...|..|.|:
Human    95 QAPSAAGVPGDVLAKSSANVY-----HHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPE-- 152

  Fly   220 EVHQNHHNM------GMYQQQSGVP------------PVGAPPQGMMHQGQGPPQMHQGHPGQHT 266
                   |:      |....:.|.|            ..|||.......|.|..........:..
Human   153 -------NLASSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAAEEK 210

  Fly   267 PPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIA 331
            ...:.|.|.||...|..:...::.....|..::.|..||:||..|||:||.|:.|:.:.:|::::
Human   211 ERRRRPESSSSPESSSGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLS 275

  Fly   332 HALCLTERQIKIWFQNRRMKWKKENKTK 359
            ..|.||:||:||||||||||.||.|:.:
Human   276 RMLNLTDRQVKIWFQNRRMKEKKINRDR 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	37/172 (22%)
		Homeodomain	298..354	CDD:459649	28/55 (51%)
HOXA11	NP_005514.1	DUF3528	25..153	CDD:432284	32/136 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..246		14/91 (15%)
		Homeodomain	242..298	CDD:459649	28/55 (51%)