Protein Alignment Antp and HOXA6

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_076919.1
• Gene: HOXA6 / 3203
• HGNCID: 5107
• Length: 233
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 99/241 - (41%)
• Similarity: 116/241 - (48%)
• Gaps: 69/241 - (28%)

  Fly   186 MSGHHMNAQM--TLP----HHMGH-PQAQLGYTDV----------GVPDVTEVHQNHHNMGMYQQ 233
            ||.:.:|...  :||    ..:|. |..|.||..:          .:||.|     :.:...|||
Human     1 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKT-----YTSPCFYQQ 60

  Fly   234 QSGVPPV-------------------GAPPQGMMHQGQGP-PQMHQGHPGQHTPPSQNPNSQSSG 278
            .:.|...                   ||.|.|...| :|| ..:|.....|:.|.|      |||
Human    61 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQ-RGPGDYLHFSPEQQYKPDS------SSG 118

  Fly   279 M-------------PSPLYPWMRSQFGKC------QERKRGRQTYTRYQTLELEKEFHFNRYLTR 324
            .             .||:||||: :...|      ...:||||||||||||||||||||||||||
Human   119 QGKALHDEGADRKYTSPVYPWMQ-RMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTR 182

  Fly   325 RRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGEGDE 370
            |||||||:|||||||||||||||||||||||||........||..|
Human   183 RRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	44/175 (25%)
		Homeodomain	298..354	CDD:459649	53/55 (96%)
HOXA6	NP_076919.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..127		12/44 (27%)
		Antp-type hexapeptide	136..141		3/4 (75%)
		Homeodomain	156..212	CDD:459649	53/55 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..233		5/15 (33%)