Protein Alignment Antp and HOXA4

DIOPT Version :9

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_002132.3
• Gene: HOXA4 / 3201
• HGNCID: 5105
• Length: 320
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 117/384 - (30%)
• Similarity: 135/384 - (35%)
• Gaps: 163/384 - (42%)

  Fly    58 PRFPPYDRMPYYNGQGMDQQQQHQVYSRPDSPSSQVGGVMPQAQTNGQLGVPQQQQQQQQQPSQN 122
            |:|||::....::|.|                              |..|.|......||.|
Human    15 PKFPPFEEYAQHSGSG------------------------------GADGGPGGGPGYQQPP--- 46

  Fly   123 QQQQQAQQAPQQLQQQLPQVTQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLVDQMS 187
                    ||.         ||.:  |.||.|.|          ..||
Human    47 --------APP---------TQHL--PLQQPQLP----------HAGG----------------- 65

  Fly   188 GHHMNAQMTLP---HHMGHPQAQL----GYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQ 245
            |....|....|   ....:|.|.|    |..|...|              |..:.|..| |.|||
Human    66 GREPTASYYAPRTAREPAYPAAALYPAHGAADTAYP--------------YGYRGGASP-GRPPQ 115

  Fly   246 GMM--HQGQGPPQ-MHQGHPGQ-HTPPSQNPNS-------------QSSGMP------------- 280
            ...  .|.:||.. :|..|..| ..||...|.:             .:.|:|
Human   116 PEQPPAQAKGPAHGLHASHVLQPQLPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLA 180

  Fly   281 --SPL---------YPWMR---------SQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRR 325
              |||         ||||:         |..|  .|.||.|..|||.|.||||||||||||||||
Human   181 DKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNG--GEPKRSRTAYTRQQVLELEKEFHFNRYLTRR 243

  Fly   326 RRIEIAHALCLTERQIKIWFQNRRMKWKKENK---TK---GEPGSGGEGDEITPPNSPQ 378
            |||||||.|||:|||:|||||||||||||::|   ||   ....|...|    ||...|
Human   244 RRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAG----PPGKAQ 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	43/201 (21%)
		Homeobox	301..354	CDD:395001	45/52 (87%)
HOXA4	NP_002132.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..77		22/136 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..168		18/81 (22%)
		Antp-type hexapeptide	194..199		3/4 (75%)
		Homeobox	218..271	CDD:278475	44/52 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	273..320		8/30 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810