Protein Alignment Antp and TLX1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: XP_011538046.1
• Gene: TLX1 / 3195
• HGNCID: 5056
• Length: 342
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 59/225 - (26%)
• Similarity: 80/225 - (35%)
• Gaps: 82/225 - (36%)

  Fly   166 AAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHH------MGHPQAQLGYTDVGVPDVTEVHQN 224
            |..||.|....|||......:|...:   :.:|.|      :.|||.    ...|:|.
Human   106 ALAGGPGPGGGGGSSGGAGALSAAGV---IRVPAHRPLAGAVAHPQP----LATGLPT------- 156

  Fly   225 HHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQ----------------------GHPGQH-T 266
                        ||.|.|.|......|...|.|..                      |||.|: |
Human   157 ------------VPSVPAMPGVNNLTGLTFPWMESNRRYTKDRFTVALSPFTVTRRIGHPYQNRT 209

  Fly   267 PPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIA 331
            ||                           ::|:.|.::||.|..||||.||..:||....|..:|
Human   210 PP---------------------------KKKKPRTSFTRLQICELEKRFHRQKYLASAERAALA 247

  Fly   332 HALCLTERQIKIWFQNRRMKWKKENKTKGE 361
            .||.:|:.|:|.||||||.||:::...:.|
Human   248 KALKMTDAQVKTWFQNRRTKWRRQTAEERE 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	32/168 (19%)
		Homeodomain	298..354	CDD:459649	28/55 (51%)
TLX1	XP_011538046.1	Homeodomain	214..270	CDD:459649	28/55 (51%)