DRSC/TRiP Functional Genomics Resources

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Protein Alignment Antp and VSX1

DIOPT Version :10

Sequence 1:NP_996167.1 Gene:Antp / 40835 FlyBaseID:FBgn0260642 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_055403.2 Gene:VSX1 / 30813 HGNCID:12723 Length:365 Species:Homo sapiens


Alignment Length:128 Identity:40/128 - (31%)
Similarity:58/128 - (45%) Gaps:13/128 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   237 VPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSG----MPSPLYPWMRSQFGKCQER 297
            :||.|..|...:...:.||.:.:.........| :.:|||..    ..||       ..|| :::
Human   109 LPPRGPEPAAPLAPSRPPPALGRQKRSDSVSTS-DEDSQSEDRNDLKASP-------TLGK-RKK 164

  Fly   298 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKG 360
            :|.|..:|.:|..||||.|....|.....|..:|....|.|.:|::||||||.||:|..|..|
Human   165 RRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWG 227

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AntpNP_996167.1 KLF1_2_4_N <161..306 CDD:425360 16/72 (22%)
Homeodomain 298..354 CDD:459649 23/55 (42%)
VSX1NP_055403.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..37
Octapeptide motif 31..38
PRK14959 <47..>149 CDD:184923 10/40 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 113..167 12/62 (19%)
Nuclear localization signal. /evidence=ECO:0000255 161..166 1/5 (20%)
Homeodomain 165..221 CDD:459649 23/55 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 290..365
Blue background indicates that the domain is not in the aligned region.

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