DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Antp and Hoxb3

DIOPT Version :9

Sequence 1:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001100512.1	Gene:	Hoxb3 / 303488	RGDID:	1310780	Length:	429	Species:	Rattus norvegicus

Alignment Length:	284	Identity:	84/284 - (29%)
Similarity:	109/284 - (38%)	Gaps:	101/284 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 QQVTHPQQQQQQPVVYASCKLQAAVGGLG-MVPEGGSPPLVDQMSGHHMN---AQMTLPHHMGHP 204
            |..||.:...|:    ::|.||:    || ..|...|    .:::|..|.   |...||...|.|
  Rat    38 QAATHLEGDYQR----SACSLQS----LGNAAPHAKS----KELNGSCMRPGLAPEPLPAPPGSP 90

  Fly   205 QAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPS 269
                                             ||..||.....:...|      |.|.:..||.
  Rat    91 ---------------------------------PPSAAPTSTTSNSNNG------GGPSKSGPPK 116

  Fly   270 QNPNSQSSGMPSPLYPWMRS--QFGKCQE------------------------------------ 296
            ...:|.|: :...::|||:.  |..|.:.
  Rat   117 CGASSNST-LTKQIFPWMKESRQTSKLKNSSPGTAEGCGGGGGGGGGGGSSSGGGGSGGGGGDKS 180

  Fly   297 ------RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE 355
                  .||.|..||..|.:||||||||||||.|.||:|:|:.|.|:||||||||||||||:||:
  Rat   181 PPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKD 245

  Fly   356 NKTKG-EPGSGGEGDEITPPNSPQ 378
            .|.|| ...|||.....:||...|
  Rat   246 QKAKGLASSSGGPSPAGSPPQPMQ 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	34/192 (18%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	37/52 (71%)
Hoxb3	NP_001100512.1	Homeobox	191..244	CDD:395001	37/52 (71%)
Hoxb3	NP_001100512.1	DUF4074	365..427	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810