DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Antp and hoxb2a

DIOPT Version :9

Sequence 1:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_571191.1	Gene:	hoxb2a / 30338	ZFINID:	ZDB-GENE-990415-103	Length:	390	Species:	Danio rerio

Alignment Length:	171	Identity:	67/171 - (39%)
Similarity:	85/171 - (49%)	Gaps:	40/171 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 APPQGMMHQGQGPPQMHQGHPGQHTPP---------------------SQNPNSQSS-----GMP 280
            |||  ..|| |||..:..|.|..|..|                     :.:|:..||     |:.
Zfish    82 APP--TQHQ-QGPAPLSGGAPLAHEFPWMKEKKSSKKCPKPGATAAAAAASPSQASSGYTTAGLE 143

  Fly   281 SPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWF 345
            ||..  ::.........:|.|..||..|.||||||||||:||.|.||:|||..|.|||||:|:||
Zfish   144 SPTE--IQGGLDNVSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWF 206

  Fly   346 QNRRMKWKKE-----NKTKGEPGSGG---EGDEITPPNSPQ 378
            ||||||.|::     :..:||| ||.   ||.:.:.|.|.|
Zfish   207 QNRRMKHKRQTTHHRDGQEGEP-SGFDLLEGTDASSPYSSQ 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	21/89 (24%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	37/52 (71%)
hoxb2a	NP_571191.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	40..73
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	81..100		9/20 (45%)
		Antp-type hexapeptide	103..108		1/4 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	108..155		6/48 (13%)
		Homeobox	162..214	CDD:278475	37/51 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	211..338		13/37 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810