Protein Alignment Antp and pitx2

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_571050.1
• Gene: pitx2 / 30164
• ZFINID: ZDB-GENE-990714-27
• Length: 314
• Species: Danio rerio
• Alignment Length: 191
• Identity: 51/191 - (26%)
• Similarity: 73/191 - (38%)
• Gaps: 49/191 - (25%)

  Fly   191 MNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGM----YQQQSGVPP----VGAPPQGM 247
            |...::|.||                     |.|||..|.    ....|.:.|    |.:..:..
Zfish     4 MKDPLSLDHH---------------------HHNHHVTGSKHAPLSMASSLQPLQRSVDSKHRLD 47

  Fly   248 MH--QGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTL 310
            :|  .....|:..:...|      |:.|..|:..||           |.:.::|.|..:|..|..
Zfish    48 VHTVSDTSSPESVEKEKG------QSKNEDSNDDPS-----------KKKRQRRQRTHFTSQQLQ 95

  Fly   311 ELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW-KKENKTKGEPGSGGEGDE 370
            |||..|..|||.....|.|||....|||.::::||:|||.|| |:|...:.|....|.|.:
Zfish    96 ELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQ 156

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	23/124 (19%)
		Homeodomain	298..354	CDD:459649	25/56 (45%)
pitx2	NP_571050.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..93		24/126 (19%)
		Homeodomain	83..139	CDD:459649	25/55 (45%)
		OAR	272..289	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	276..289
		Nuclear localization signal. /evidence=ECO:0000255	282..286