Protein Alignment Antp and TLX3

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_066305.2
• Gene: TLX3 / 30012
• HGNCID: 13532
• Length: 291
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 56/224 - (25%)
• Similarity: 82/224 - (36%)
• Gaps: 67/224 - (29%)

  Fly   168 VGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQ 232
            :||    |.||.|...                   :|.....:..:|.|        ..:.|.|.
Human    44 LGG----PPGGRPGAT-------------------YPSLPASFAGLGAP--------FEDAGSYS 77

  Fly   233 QQSGVPPVGA--PPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRS--QFGK 293
            ....:.|.|.  .|......|..||.:....|..   ||....|...|:.   :|||.|  :|.|
Human    78 VNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAM---PSVPTVSSLGGLN---FPWMESSRRFVK 136

  Fly   294 CQ--------------------------ERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAH 332
            .:                          :||:.|.:::|.|..||||.||..:||....|..:|.
Human   137 DRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAK 201

  Fly   333 ALCLTERQIKIWFQNRRMKWKKENKTKGE 361
            :|.:|:.|:|.||||||.||:::...:.|
Human   202 SLKMTDAQVKTWFQNRRTKWRRQTAEERE 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	31/167 (19%)
		Homeodomain	298..354	CDD:459649	26/55 (47%)
TLX3	NP_066305.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		6/34 (18%)
		Homeodomain	167..223	CDD:459649	26/55 (47%)