Protein Alignment Antp and Nkx1-1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: XP_234082.6
• Gene: Nkx1-1 / 298981
• RGDID: 1564874
• Length: 443
• Species: Rattus norvegicus
• Alignment Length: 280
• Identity: 69/280 - (24%)
• Similarity: 97/280 - (34%)
• Gaps: 95/280 - (33%)

  Fly    99 QAQTNGQ---LGVPQQQQQQQQQPSQNQQQQQAQQAPQQLQQQLPQVTQQVTHPQQQQQQPVVYA 160
            :|:.||.   .|.......:.:.|.:::.:.||           |:| |.|...::
  Rat   167 EAEANGYSSGSGRSPTADSEDEAPEEDEDEDQA-----------PEV-QDVQGTEE--------- 210

  Fly   161 SCKLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNH 225
                          |.|||                          ..||....|.....||
  Rat   211 --------------PRGGS--------------------------GGLGARGSGCSGAAEV---- 231

  Fly   226 HNMGMYQQQSGVPPVGAP-PQGMMHQGQGPPQMHQGHPGQHTPP-----SQNPNSQSSGMPSPLY 284
                   :.|.|....|| |:|......|||....|.....:.|     :..|..:.:|..|
  Rat   232 -------EASPVDEAAAPGPRGNSPGAPGPPVTAAGAGNAGSTPQGAAVATKPKRKRTGSDS--- 286

  Fly   285 PWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRR 349
                    |..:.:|.|..:|..|.:.||.:|...|||:...|:.:|.:|.|||.|:||||||||
  Rat   287 --------KSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRR 343

  Fly   350 MKWKKEN---KTKGEPGSGG 366
            .||||:|   .|....|.||
  Rat   344 TKWKKQNPGADTSAPTGGGG 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	26/150 (17%)
		Homeodomain	298..354	CDD:459649	27/55 (49%)
Nkx1-1	XP_234082.6	Homeodomain	292..348	CDD:459649	27/55 (49%)