DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Antp and Hoxd4

DIOPT Version :9

Sequence 1:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001099355.1	Gene:	Hoxd4 / 288153	RGDID:	1309690	Length:	251	Species:	Rattus norvegicus

Alignment Length:	240	Identity:	88/240 - (36%)
Similarity:	101/240 - (42%)	Gaps:	81/240 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 MSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQ 250
            ||.:.:|::               |.|...|...|..|     |.|..:.|....|:..||...|
  Rat     3 MSSYMVNSK---------------YVDPKFPPCEEYLQ-----GGYLGEQGADYYGSGAQGSDFQ 47

  Fly   251 ------------------GQGP---------------PQMHQGHPG------------------Q 264
                              |.||               |..|...||                  |
  Rat    48 PPGLYPRPDFGEQPFGGGGPGPGSALPARGHGQEPSGPGSHYSAPGEPCPAPPPAPLPGARACSQ 112

  Fly   265 HTPPSQNPNSQSSGMPSPLYPWMRSQFGKC-------QERKRGRQTYTRYQTLELEKEFHFNRYL 322
            .|.|.|.|...:...|:.:||||:......       .|.||.|..|||.|.|||||||||||||
  Rat   113 PTGPKQPPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYL 177

  Fly   323 TRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENK---TKGEPGS 364
            ||||||||||.|||:|||||||||||||||||::|   |||...|
  Rat   178 TRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSS 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	37/177 (21%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	46/52 (88%)
Hoxd4	NP_001099355.1	Homeobox	155..209	CDD:395001	46/53 (87%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810