Protein Alignment Antp and tlx1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_739571.1
• Gene: tlx1 / 266964
• ZFINID: ZDB-GENE-021021-2
• Length: 301
• Species: Danio rerio
• Alignment Length: 260
• Identity: 65/260 - (25%)
• Similarity: 99/260 - (38%)
• Gaps: 73/260 - (28%)

  Fly   134 QLQQQLPQVTQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPL-----VDQMSGHHMNA 193
            |:.....|.:..:|:|:.|.   :.|          |||.:.......:     |:..||::.|:
Zfish    22 QILNNADQGSCMITNPRMQD---LDY----------GLGCIVSTAYNTMTGNYNVNNSSGYNGNS 73

  Fly   194 QMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMH 258
            .....::|     .||         ..|:.|..|      .|||..|.|      |:..|  .:|
Zfish    74 CSVGSYNM-----NLG---------ANVNGNCLN------SSGVIRVPA------HRPLG--SVH 110

  Fly   259 QGHP-GQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQER------------------------- 297
            ...| ...|.||.......:.:....:|||.|.....::|
Zfish   111 SSIPTSAATVPSMGSMGTINNLTGLTFPWMESNRRYTKDRFTVALSPFTVTRRIGHPYQNRTPPK 175

  Fly   298 -KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGE 361
             |:.|.::||.|..||||.||..:||....|..:|.||.:|:.|:|.||||||.||:::...:.|
Zfish   176 KKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEERE 240

  Fly   362  361
            Zfish   241  240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	32/176 (18%)
		Homeodomain	298..354	CDD:459649	28/55 (51%)
tlx1	NP_739571.1	Homeodomain	177..233	CDD:459649	28/55 (51%)