Protein Alignment Antp and NKX2-8

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_055175.2
• Gene: NKX2-8 / 26257
• HGNCID: 16364
• Length: 239
• Species: Homo sapiens
• Alignment Length: 172
• Identity: 47/172 - (27%)
• Similarity: 66/172 - (38%)
• Gaps: 43/172 - (25%)

  Fly   243 PPQGMMHQGQGPPQMHQGHPGQ----------HTPPSQNPNSQSSGMPSPLYPWMR--SQFGKCQ 295
            |.|...|..:..|:.....|..          |.|.|...:.::|...|...|..|  |.....:
Human    18 PEQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAE 82

  Fly   296 ERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENK--- 357
            :||:.|..:::.||||||:.|...|||:...|.::|..|.||..|:||||||.|.|.|:...
Human    83 KRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPGA 147

  Fly   358 ----------------------------TKGEPGSGGEGDEI 371
                                        ..|:|..||.|.|:
Human   148 AESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEV 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	16/74 (22%)
		Homeodomain	298..354	CDD:459649	26/55 (47%)
NKX2-8	NP_055175.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..87		15/68 (22%)
		Homeodomain	85..141	CDD:459649	26/55 (47%)