Protein Alignment Antp and ALX3

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_006483.2
• Gene: ALX3 / 257
• HGNCID: 449
• Length: 343
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 58/250 - (23%)
• Similarity: 82/250 - (32%)
• Gaps: 89/250 - (35%)

  Fly   174 VPEGGSPP---LVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQS 235
            :||...||   |.|...|..:|.                              .|...|..:.:.
Human    61 LPEPAKPPAKYLQDLGPGPALNG------------------------------GHFYEGPAEAEE 95

  Fly   236 GVPPVGAPPQGMMHQGQGP---PQMHQGHPGQ-----HTPPSQNPNSQSSGMPSPLYPWMRSQFG 292
            ......:.||..:....||   |...||.||.     |.|       .|.|:|..:      :..
Human    96 KTSKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHLP-------LSPGLPDSM------ELA 147

  Fly   293 KCQERK-RGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK-- 354
            |.:.:| |.|.|::.:|..||||.|....|.....|.::|....|||.::::||||||.||:|
Human   148 KNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRE 212

  Fly   355 ------------------------------ENKTKGEPGSGGEGDE--ITPPNSP 377
                                          :|.....||||..|..  ::|...|
Human   213 RYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGSPGGPCLVSPEGIP 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	29/143 (20%)
		Homeodomain	298..354	CDD:459649	24/56 (43%)
ALX3	NP_006483.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..104		10/72 (14%)
		PRK12323	<13..131	CDD:481241	19/99 (19%)
		Homeodomain	154..210	CDD:459649	23/55 (42%)