Protein Alignment Antp and Alx1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_037053.1
• Gene: Alx1 / 25401
• RGDID: 2273
• Length: 326
• Species: Rattus norvegicus
• Alignment Length: 214
• Identity: 51/214 - (23%)
• Similarity: 76/214 - (35%)
• Gaps: 55/214 - (25%)

  Fly   148 HPQQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTD 212
            |..:.......|........|...|.:|.          :.||:....|.|  ........|.|.
  Rat    30 HVMETLDNESFYGKATAGKCVQAFGPLPR----------AEHHVRLDRTSP--CQDSSVNYGITK 82

  Fly   213 V-GVPDVTEVHQ---NHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPN 273
            | |.|..||:::   ..:|:.|           :|.:||      |.:......|...    :.|
  Rat    83 VEGQPLHTELNRAMDGCNNLRM-----------SPVKGM------PEKSELDELGDKC----DSN 126

  Fly   274 SQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTE 338
            ..||                  :::|.|.|:|..|..||||.|....|.....|.::|....|||
  Rat   127 VSSS------------------KKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTE 173

  Fly   339 RQIKIWFQNRRMKWKKENK 357
            .::::||||||.||:|..:
  Rat   174 ARVQVWFQNRRAKWRKRER 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	27/148 (18%)
		Homeodomain	298..354	CDD:459649	24/55 (44%)
Alx1	NP_037053.1	Homeodomain	133..189	CDD:459649	24/55 (44%)
		Transactivation domain. /evidence=ECO:0000269|PubMed:12390248	192..326		0/1 (0%)
		OAR	302..320	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	306..319