Protein Alignment Antp and Tlx1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: XP_006526978.1
• Gene: Tlx1 / 21908
• MGIID: 98769
• Length: 345
• Species: Mus musculus
• Alignment Length: 284
• Identity: 61/284 - (21%)
• Similarity: 85/284 - (29%)
• Gaps: 129/284 - (45%)

  Fly   198 PHHMGHPQAQLGYTD---------VGVPD-------VTEVHQNHHNM-----GMYQQQSGVPPVG 241
            |||: ||    |:.:         :..||       .:.:....:.:     |.|....|....|
Mouse     6 PHHL-HP----GHAEPISFGIDQILNSPDQGGCMGPASRLQDGDYGLGCLVGGAYTYGGGGSAAG 65

  Fly   242 APPQGMMHQGQGPPQMHQGHPGQHT------------PPSQNPNSQSSGMPSP------------ 282
            |...|....|.|.|    |.||...            |.|.|.|...:|.|.|
Mouse    66 AGAGGTGAYGAGGP----GGPGGPAGGGGGACSMGPLPGSYNVNMALAGGPGPGGGGGGGGAGGA 126

  Fly   283 -------------------------------------------------LYPWMRSQFGKCQER- 297
                                                             .:|||.|.....::|
Mouse   127 GALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAVPGVNNLTGLTFPWMESNRRYTKDRF 191

  Fly   298 -------------------------KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLT 337
                                     |:.|.::||.|..||||.||..:||....|..:|.||.:|
Mouse   192 TVALSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMT 256

  Fly   338 ERQIKIWFQNRRMKWKKENKTKGE 361
            :.|:|.||||||.||:::...:.|
Mouse   257 DAQVKTWFQNRRTKWRRQTAEERE 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	34/227 (15%)
		Homeodomain	298..354	CDD:459649	28/55 (51%)
Tlx1	XP_006526978.1	Homeodomain	217..273	CDD:459649	28/55 (51%)