Protein Alignment Antp and EVX1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001980.1
• Gene: EVX1 / 2128
• HGNCID: 3506
• Length: 407
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 73/277 - (26%)
• Similarity: 107/277 - (38%)
• Gaps: 74/277 - (26%)

  Fly   104 GQLGVPQQQQQQQQQPSQNQQQQQAQQAPQQLQQQLPQ--VTQQVTHPQQQ-------QQQPV-- 157
            ||||....::      ..|..:......|:..::.:|:  ::.:...|..:       :::||
Human    14 GQLGTLVGKR------VSNLSEAVGSPLPEPPEKMVPRGCLSPRAVPPATRERGGGGPEEEPVDG 72

  Fly   158 ---VYASCKLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLG----YTDVGV 215
               ..|....:..|.|..|:..|...|.||.:||            .|.|.:...    |.::.|
Human    73 LAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSG------------QGQPSSSDTESDFYEEIEV 125

  Fly   216 ---PD-VTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQS 276
               || .|...:..|:.|     ||...:...|.|                |..||.| |..|..
Human   126 SCTPDCATGNAEYQHSKG-----SGSEALVGSPNG----------------GSETPKS-NGGSGG 168

  Fly   277 SGMPSPLYPWMRSQFGKC---QERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTE 338
            .|....|         .|   .:.:|.|..:||.|...|||||:...|::|.||.|:|.||.|.|
Human   169 GGSQGTL---------ACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPE 224

  Fly   339 RQIKIWFQNRRMKWKKE 355
            ..||:||||||||.|::
Human   225 TTIKVWFQNRRMKDKRQ 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	33/155 (21%)
		Homeodomain	298..354	CDD:459649	30/55 (55%)
EVX1	NP_001980.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..120		17/102 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..179		15/72 (21%)
		Homeodomain	184..240	CDD:459649	30/55 (55%)