Protein Alignment Antp and EMX1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 65/265 - (24%)
• Similarity: 88/265 - (33%)
• Gaps: 104/265 - (39%)

  Fly   148 HPQQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTD 212
            ||...:   ..:.|....||..|.|....|| |.||             .|..|.||
Human    87 HPSAAE---AAFVSGFPAAAAAGAGRSLYGG-PELV-------------FPEAMNHP-------- 126

  Fly   213 VGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSS 277
                 ...||..|        |.|..|:..|              |.....||..|..
Human   127 -----ALTVHPAH--------QLGASPLQPP--------------HSFFGAQHRDPLH------- 157

  Fly   278 GMPSPLYPW-MRSQF------------------GK-CQERKRGRQTYTRYQTLELEKEFHFNRYL 322
                 .||| :|::|                  |. .::.||.|..::..|.|.||:.|..|.|:
Human   158 -----FYPWVLRNRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYV 217

  Fly   323 TRRRRIEIAHALCLTERQIKIWFQNRRMKWKK----------ENKTKGE----------PGSGGE 367
            ....|.::|.:|.|:|.|:|:||||||.|:|:          |.|.||.          ..:.||
Human   218 VGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGE 282

  Fly   368 GDEIT 372
            ..::|
Human   283 DIDVT 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	34/164 (21%)
		Homeodomain	298..354	CDD:459649	24/55 (44%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		7/39 (18%)