Protein Alignment Antp and Nkx2-3

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_032725.1
• Gene: Nkx2-3 / 18089
• MGIID: 97348
• Length: 362
• Species: Mus musculus
• Alignment Length: 222
• Identity: 53/222 - (23%)
• Similarity: 82/222 - (36%)
• Gaps: 52/222 - (23%)

  Fly   191 MNAQMTLPHHMGHPQAQL-----------------GYTDVGVPDVTEVHQNHHNMGMYQQQSGVP 238
            :|.:.....|..|.||:|                 .::|.|..|..|..:....:.......|..
Mouse    18 LNLEQQRHFHGAHLQAELEQHFHSAPCMLATAEGTQFSDAGEEDEEEEGEKLSYLNSLAAAEGHG 82

  Fly   239 PVGAPPQGMMH-----QGQGPPQMHQGHPGQHTPPS-----------QNPNSQSSGMPSPLYPWM 287
            ..|..||..:|     ...||.:..:....:.:..|           ....|:....|.|
Mouse    83 DSGLCPQSYVHTVLRDACSGPKEQEEEVVSERSQKSCQLKKSLEAAGDCKTSEDGERPKP----- 142

  Fly   288 RSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 352
                   :.|::.|..:::.|..|||:.|...|||:...|..:|.:|.||..|:||||||||.|.
Mouse   143 -------RSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKC 200

  Fly   353 KKENKTKG-EPGSGGEGDEITPPNSPQ 378
            |::.:.|. |.|:.      .||..|:
Mouse   201 KRQRQDKSLELGTH------APPPPPR 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	23/147 (16%)
		Homeodomain	298..354	CDD:459649	24/55 (44%)
Nkx2-3	NP_032725.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..149		4/34 (12%)
		Homeodomain	146..202	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..222		6/25 (24%)