Protein Alignment Antp and Msx1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_034965.2
• Gene: Msx1 / 17701
• MGIID: 97168
• Length: 303
• Species: Mus musculus
• Alignment Length: 221
• Identity: 59/221 - (26%)
• Similarity: 84/221 - (38%)
• Gaps: 49/221 - (22%)

  Fly   167 AVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMY 231
            |.||:|..| |.:......|......|:..:|..:             :|...|.....|.....
Mouse    25 AGGGVGQAP-GAAAATATAMGTDEEGAKPKVPASL-------------LPFSVEALMADHRKPGA 75

  Fly   232 QQQSGVPPVGAPPQG--MMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGM-------------PS 281
            ::...|...||...|  :.|.|..|..:  |.|...:.|....:....|:             |.
Mouse    76 KESVLVASEGAQAAGGSVQHLGTRPGSL--GAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPE 138

  Fly   282 PL--YPWMRS-QFG----------KCQERK-----RGRQTYTRYQTLELEKEFHFNRYLTRRRRI 328
            .|  .|||:| :|.          .|..||     :.|..:|..|.|.||::|...:||:...|.
Mouse   139 KLDRTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERA 203

  Fly   329 EIAHALCLTERQIKIWFQNRRMKWKK 354
            |.:.:|.|||.|:||||||||.|.|:
Mouse   204 EFSSSLSLTETQVKIWFQNRRAKAKR 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	34/171 (20%)
		Homeodomain	298..354	CDD:459649	26/60 (43%)
Msx1	NP_034965.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..53		8/28 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..112		6/23 (26%)
		PTZ00449	<99..>248	CDD:185628	41/133 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	135..163		7/27 (26%)
		Homeodomain	173..229	CDD:459649	25/55 (45%)