DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Antp and nob-1

DIOPT Version :9

Sequence 1:NP_996167.1 Gene:Antp / 40835 FlyBaseID:FBgn0260642 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_001369824.1 Gene:nob-1 / 176641 WormBaseID:WBGene00003779 Length:243 Species:Caenorhabditis elegans


Alignment Length:264 Identity:71/264 - (26%)
Similarity:106/264 - (40%) Gaps:47/264 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   124 QQQQAQQAPQQLQQQLPQVTQQVTHPQQQQQQPVVYASC-----KLQAAVGGLGMVPEGGSPPLV 183
            ||.....:|:..::.:..|          ||.|..:.|.     .:|...........|.||.|.
 Worm     6 QQMINNDSPEDSKESITSV----------QQTPFFWPSAAAAIPSIQGESRSERESETGSSPQLA 60

  Fly   184 DQMSGHHMNAQMTLPHHMG----HPQAQLGYTDVGV---PDVTEVHQNH-HNMGMYQQQSGVPPV 240
            ...:|      |.:|...|    .|.......:.|:   |..|:.:||. .:.|.|.       .
 Worm    61 PSSTG------MVMPGTAGMYGFGPSRMPTANEFGMMMNPVYTDFYQNPLASTGWYS-------Y 112

  Fly   241 GAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLY-PWMRSQFGKCQERKRGRQTY 304
            |.|.|  .......|.: .|:....|.|:...:|.::...:.:: ||..|..|     |:.||.|
 Worm   113 GQPYQ--FTANYSIPSL-DGNLSDITIPTTAGSSAATTPNAAMHLPWAISHDG-----KKKRQPY 169

  Fly   305 TRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGEGD 369
            .:.|...||.|:..|:|||.:||.|::..|.|.|:|:|:||||||||.||..:....|..  .|.
 Worm   170 KKDQISRLEYEYSVNQYLTNKRRSELSAQLMLDEKQVKVWFQNRRMKDKKLRQRHSGPFP--HGA 232

  Fly   370 EITP 373
            .:||
 Worm   233 PVTP 236

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AntpNP_996167.1 KLF1_2_4_N <161..306 CDD:425360 34/158 (22%)
Homeobox 301..354 CDD:395001 27/52 (52%)
nob-1NP_001369824.1 Homeobox 165..219 CDD:395001 27/53 (51%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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