Protein Alignment Antp and DLX6

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_005213.3
• Gene: DLX6 / 1750
• HGNCID: 2919
• Length: 293
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 78/279 - (27%)
• Similarity: 102/279 - (36%)
• Gaps: 67/279 - (24%)

  Fly   111 QQQQQQQQPSQNQQQQQAQQAPQQLQQQLPQVTQQVTHPQQQQQQPVVYA---------SCKLQA 166
            ||||||||  |.|||||.||.|.......||       |..||..|.:..         |....|
Human    26 QQQQQQQQ--QQQQQQQQQQQPPPPPPPPPQ-------PHSQQSSPAMAGAHYPLHCLHSAAAAA 81

  Fly   167 AVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMY 231
            |.|                 |.||.:.|   .||.|.|.|..|...          .||.::..|
Human    82 AAG-----------------SHHHHHHQ---HHHHGSPYASGGGNS----------YNHRSLAAY 116

  Fly   232 QQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQF-GKCQ 295
            .              .|...|..|.:...|  ..:..:|.....:....:.:......:| ||.:
Human   117 P--------------YMSHSQHSPYLQSYH--NSSAAAQTRGDDTDQQKTTVIENGEIRFNGKGK 165

  Fly   296 ERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKG 360
            :.::.|..|:..|...|...|...:||....|.|:|.:|.||:.|:||||||:|.|:||..|...
Human   166 KIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGS 230

  Fly   361 EPGSGG--EGDEITPPNSP 377
            .|....  :|.....|.||
Human   231 NPHESDPLQGSAALSPRSP 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	27/145 (19%)
		Homeodomain	298..354	CDD:459649	22/55 (40%)
DLX6	NP_005213.3	Homeodomain	168..224	CDD:459649	22/55 (40%)