Protein Alignment Antp and DLX2

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_004396.1
• Gene: DLX2 / 1746
• HGNCID: 2915
• Length: 328
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 70/277 - (25%)
• Similarity: 102/277 - (36%)
• Gaps: 70/277 - (25%)

  Fly   105 QLGVPQQQQQQQQQPS-------QNQQQQQAQQAPQQLQQQLPQVTQQVTHPQQQQQQPVVYASC 162
            |:.......|.||.||       .|.....:...||: ...||..|...:.....||.|
Human    16 QIAASSTYHQHQQPPSGGGAGPGGNSSSSSSLHKPQE-SPTLPVSTATDSSYYTNQQHP------ 73

  Fly   163 KLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHN 227
                |.||.|    ||||..                 |||..|    |...|:.:|....::.::
Human    74 ----AGGGGG----GGSPYA-----------------HMGSYQ----YQASGLNNVPYSAKSSYD 109

  Fly   228 MGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFG 292
            :|.....:...|.|.                     ..:|.:..|..:.      |.|.:|...|
Human   110 LGYTAAYTSYAPYGT---------------------SSSPANNEPEKED------LEPEIRIVNG 147

  Fly   293 KCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENK 357
            |.::.::.|..|:.:|...|::.|...:||....|.|:|.:|.||:.|:||||||||.|:||..|
Human   148 KPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWK 212

  Fly   358 TKGEPGSGGEGDEITPP 374
            :...|.....|...:||
Human   213 SGEIPSEQHPGASASPP 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	27/144 (19%)
		Homeodomain	298..354	CDD:459649	23/55 (42%)
DLX2	NP_004396.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..81		19/79 (24%)
		DLL_N	51..132	CDD:463567	26/137 (19%)
		Homeodomain	153..209	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	211..270		5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..328