Protein Alignment Antp and GSX2

DIOPT Version :9

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_573574.2
• Gene: GSX2 / 170825
• HGNCID: 24959
• Length: 304
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 83/325 - (25%)
• Similarity: 103/325 - (31%)
• Gaps: 151/325 - (46%)

  Fly   140 PQVTQQVTHPQQQQQQPVVYASCKL---------QAAVG------GLGMVPEGGS---------P 180
            |.:...|:.|....::...:..|.|         :.:||      |.|:...|||         |
Human    39 PPLVMSVSGPGCPSRKSGAFCVCPLCVTSHLHSSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALP 103

  Fly   181 PLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQ 245
            .|..|.|....:||.                   .|.|...|.:||                |||
Human   104 LLKGQFSSAPGDAQF-------------------CPRVNHAHHHHH----------------PPQ 133

  Fly   246 GMMHQGQGPPQM------------------HQGHPGQHTP------------------------P 268
            ...|..|  ||.                  ..|||..|.|                        .
Human   134 HHHHHHQ--PQQPGSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTYNVADPRRFHCLTMGGSDA 196

  Fly   269 SQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHA 333
            ||.||.                       ||.|..:|..|.||||:||..|.||:|.||||||..
Human   197 SQVPNG-----------------------KRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATY 238

  Fly   334 LCLTERQIKIWFQNRRMKWKKENK-------------------TKGE------PGSGGEGDEITP 373
            |.|:|:|:||||||||:|.|||.|                   .:.|      |.|..:..||:|
Human   239 LNLSEKQVKIWFQNRRVKHKKEGKGTQRNSHAGCKCVGSQVHYARSEDEDSLSPASANDDKEISP 303

  Fly   374  373
            Human   304  303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	39/210 (19%)
		Homeobox	301..354	CDD:395001	32/52 (62%)
GSX2	NP_573574.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..151		14/71 (20%)
		Homeobox	206..258	CDD:306543	32/51 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..304		6/21 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810