DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Antp and Lmx1b

DIOPT Version :9

Sequence 1:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	XP_006497809.1	Gene:	Lmx1b / 16917	MGIID:	1100513	Length:	408	Species:	Mus musculus

Alignment Length:	128	Identity:	34/128 - (26%)
Similarity:	49/128 - (38%)	Gaps:	26/128 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   268 PSQNPNSQSSGMPSPLYPWMRSQFGKCQER-KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIA 331
            |::...|||.|         ....||...| ||.|...|..|....:..|..:....|:.|..:|
Mouse   204 PAKGQGSQSKG---------SGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLA 259

  Fly   332 HALCLTERQIKIWFQNRRMKWKK----ENKTKGEPGSGGEGDEI------------TPPNSPQ 378
            ....|:.|.:::||||:|.|.||    ..:.:.:..|...|.|:            ||...||
Mouse   260 AETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQ 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	11/38 (29%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	15/52 (29%)
Lmx1b	XP_006497809.1	LIM1_Lmx1b	62..114	CDD:188757
		LIM2_Lmx1a_Lmx1b	121..175	CDD:188764
		Homeobox	228..282	CDD:365835	15/53 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3844
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030