DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Antp and Hoxd1

DIOPT Version :9

Sequence 1:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_034597.2	Gene:	Hoxd1 / 15429	MGIID:	96201	Length:	328	Species:	Mus musculus

Alignment Length:	266	Identity:	78/266 - (29%)
Similarity:	102/266 - (38%)	Gaps:	80/266 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 LPQVTQQVT--HPQQQQQQPVV------YASCKLQAAVGGLGMVPEG-------GSPPLVDQMSG 188
            ||..|.:.|  .|....|.||.      ||.|.|:.|. ..|..|..       ||.|..|
Mouse    57 LPLATARPTPSPPAGPAQSPVPQPAAPRYAPCTLEGAY-ERGAAPASAAEYGFLGSGPAFD---- 116

  Fly   189 HHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMY--------QQQSGVPPVGAPPQ 245
                    .|..:|....:.|           .|.::....::        ..|......|.|
Mouse   117 --------FPGALGRAADEGG-----------AHVHYATSAVFSGGGSFLLSGQVDFAAFGEP-- 160

  Fly   246 GMMHQGQGP-----PQMHQGHPG--QHTPPS----QNPNSQSSGMPS--PLYPWMR--------- 288
                   ||     .:...||||  |...|:    ..|.|.:|.:|:  ..:.||:
Mouse   161 -------GPFPACLKEPADGHPGPFQTVSPAPGACPKPASPTSSLPAAHSTFEWMKVKRNAPKKS 218

  Fly   289 --SQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 351
              |::|........|..::..|..|||||||||:||||.||||||:.|.|.:.|:||||||||||
Mouse   219 KLSEYGATSPPSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLQLNDTQVKIWFQNRRMK 283

  Fly   352 WKKENK 357
            .||..:
Mouse   284 QKKRER 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	33/183 (18%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	34/52 (65%)
Hoxd1	NP_034597.2	PRK04233	59..>105	CDD:305134	13/46 (28%)
		Antp-type hexapeptide	204..209		1/4 (25%)
		Homeobox	233..285	CDD:278475	34/51 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	304..328
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810