Protein Alignment Antp and Hoxa11

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_034580.1
• Gene: Hoxa11 / 15396
• MGIID: 96172
• Length: 313
• Species: Mus musculus
• Alignment Length: 280
• Identity: 77/280 - (27%)
• Similarity: 113/280 - (40%)
• Gaps: 47/280 - (16%)

  Fly   119 PSQNQQQQQAQQAPQQLQQQLPQV--TQQVT------------HPQQQ-----QQQPVVYASCKL 164
            ||...|...::.........||||  .::||            ||:..     ..:.:|:..| |
Mouse    32 PSFLPQTPSSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRDC-L 95

  Fly   165 QA--AVGGLGMVPEGGSPPLVDQMSGHH------MNAQMTLPHHMGHPQA--QLGYTDVGVPD-- 217
            ||  |.|..|.|....|..:.     ||      .|...|:..:...|||  |...|..|.|:
Mouse    96 QAPSAAGVPGDVLAKSSANVY-----HHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENL 155

  Fly   218 VTEVHQNHHNMGMYQQQS--------GVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNS 274
            .:..:....|.....|.:        .....|||.......|.|..  .|....:.....:.|.|
Mouse   156 ASSDYPGDKNAEKGPQAAAATSAAAVAAAATGAPATSSSDGGGGGG--CQEAAAEEKERRRRPES 218

  Fly   275 QSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTER 339
            .||...|..:...::.....|..::.|..||:||..|||:||.|:.|:.:.:|::::..|.||:|
Mouse   219 SSSPESSSGHTEDKAGGSGGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDR 283

  Fly   340 QIKIWFQNRRMKWKKENKTK 359
            |:||||||||||.||.|:.:
Mouse   284 QVKIWFQNRRMKEKKINRDR 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	36/164 (22%)
		Homeodomain	298..354	CDD:459649	28/55 (51%)
Hoxa11	NP_034580.1	DUF3528	26..154	CDD:432284	32/127 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..246		11/59 (19%)
		Homeodomain	242..298	CDD:459649	28/55 (51%)