Protein Alignment Antp and Hhex

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_032271.1
• Gene: Hhex / 15242
• MGIID: 96086
• Length: 271
• Species: Mus musculus
• Alignment Length: 132
• Identity: 45/132 - (34%)
• Similarity: 61/132 - (46%)
• Gaps: 33/132 - (25%)

  Fly   254 PPQMHQG---HPGQHTPPSQNPNSQSSGMPSPLYPWMRS------------QFGK---------- 293
            |..:|..   ||......:..|    ||...||||:.|:            ..||
Mouse    73 PTPVHPAFSHHPAAALAAAYGP----SGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQR 133

  Fly   294 -CQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW---KK 354
             ..:||.|:..::..||:||||:|...:||:...|..:|..|.|:|||:|.||||||.||   |:
Mouse   134 PLHKRKGGQVRFSNDQTVELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQ 198

  Fly   355 EN 356
            ||
Mouse   199 EN 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	17/77 (22%)
		Homeodomain	298..354	CDD:459649	27/58 (47%)
Hhex	NP_032271.1	Interaction with SOX13. /evidence=ECO:0000250|UniProtKB:Q03014	1..138		14/68 (21%)
		Required for WNT signaling induction. /evidence=ECO:0000250|UniProtKB:Q03014	138..271		31/63 (49%)
		Homeodomain	143..195	CDD:459649	25/51 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..271		3/6 (50%)