Protein Alignment Antp and Nkx6-2

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_899071.2
• Gene: Nkx6-2 / 14912
• MGIID: 1352738
• Length: 277
• Species: Mus musculus
• Alignment Length: 228
• Identity: 60/228 - (26%)
• Similarity: 94/228 - (41%)
• Gaps: 45/228 - (19%)

  Fly   175 PEGGSPPLVDQMSGHHMNAQMTL--PHH----MGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQ 233
            |.|...|.:..     :.||:.|  ||.    :|.|....|...:|  .:..::....:.|:|..
Mouse    37 PAGFKTPALGS-----LGAQLPLGTPHGISDILGRPVGAAGGGLLG--SLPRLNGLASSAGVYFG 94

  Fly   234 QSGVPPVGAPPQGMMHQGQGP---PQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQ 295
            .:.....|.|.......|:.|   |.:.||.|.:  .|....::|:.|:           ..|..
Mouse    95 PAAAVARGYPKPLAELPGRPPIFWPGVVQGSPWR--DPRLAGSAQAGGV-----------LDKDG 146

  Fly   296 ERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEN---- 356
            ::|..|.|::..|...|||.|...:||....|..:|::|.:||.|:|:||||||.||:|.:
Mouse   147 KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEM 211

  Fly   357 ---KTKGEPGS-----GG----EGDEITPPNSP 377
               |.|.:..:     ||    :.||...|..|
Mouse   212 ASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDP 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	29/139 (21%)
		Homeodomain	298..354	CDD:459649	25/55 (45%)
Nkx6-2	NP_899071.2	Homeodomain	147..205	CDD:459649	25/57 (44%)