Protein Alignment Antp and GSC

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_776248.1
• Gene: GSC / 145258
• HGNCID: 4612
• Length: 257
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 59/260 - (22%)
• Similarity: 93/260 - (35%)
• Gaps: 77/260 - (29%)

  Fly   140 PQVTQQVTHPQQQQQQPVVYASC---KLQAAVGGLG----------MVPEGGSPPLVDQMSGHHM 191
            |:....|.........|||:.:.   .|..|.||..          :.|.|...|..  :||
Human    16 PRCKDSVLPVAHSAAAPVVFPALHGDSLYGASGGASSDYGAFYPRPVAPGGAGLPAA--VSG--- 75

  Fly   192 NAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVG------APPQGMMHQ 250
                          ::|||             |::..|....|:.  |||      .||.|....
Human    76 --------------SRLGY-------------NNYFYGQLHVQAA--PVGPACCGAVPPLGAQQC 111

  Fly   251 GQGPPQMHQGHPGQHTPPS-QNPNS-QSSGMPSPLYPWM------RSQFG-----KCQERKRGRQ 302
            ...|           |||. :.|.| ..|.:|..:.|:|      |::..     .|:.::|.|.
Human   112 SCVP-----------TPPGYEGPGSVLVSPVPHQMLPYMNVGTLSRTELQLLNQLHCRRKRRHRT 165

  Fly   303 TYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGE 367
            .:|..|...||..|...:|.....|.::|..:.|.|.::::||:|||.||:::.::..|.....|
Human   166 IFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQKRSSSEESENAE 230

  Fly   368  367
            Human   231  230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	35/176 (20%)
		Homeodomain	298..354	CDD:459649	19/55 (35%)
GSC	NP_776248.1	Homeodomain	161..217	CDD:459649	19/55 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	213..257		4/18 (22%)