Protein Alignment Antp and En2

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_034264.1
• Gene: En2 / 13799
• MGIID: 95390
• Length: 324
• Species: Mus musculus
• Alignment Length: 237
• Identity: 64/237 - (27%)
• Similarity: 84/237 - (35%)
• Gaps: 72/237 - (30%)

  Fly   144 QQVTHPQQQQQQPVVYASC--KLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQA 206
            :|:...::.:..|....|.  .|.||.|...:..||||..|     ..|..|:..     |.|..
Mouse   112 EQLLGARESRPNPACAPSAGGTLSAAAGDPAVDGEGGSKTL-----SLHGGAKKP-----GDPGG 166

  Fly   207 Q---------LGYTDVGVPDVTEVHQNHHNMG---------MY-QQQSGVPPVGAPPQGMMHQGQ 252
            .         ||..|:.|...::..|....:|         :| .:.|..|..|
Mouse   167 SLDGVLKARGLGGGDLSVSSDSDSSQASATLGAQPMLWPAWVYCTRYSDRPSSG----------- 220

  Fly   253 GPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFH 317
                     |....|..:|||                     :|.||.|..:|..|...|:.||.
Mouse   221 ---------PRSRKPKKKNPN---------------------KEDKRPRTAFTAEQLQRLKAEFQ 255

  Fly   318 FNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTK 359
            .|||||.:||..:|..|.|.|.||||||||:|.|.||....|
Mouse   256 TNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNK 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	33/165 (20%)
		Homeodomain	298..354	CDD:459649	29/55 (53%)
En2	NP_034264.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..174		16/71 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..240		10/65 (15%)
		Homeodomain	236..292	CDD:459649	29/55 (53%)
		Engrail_1_C_sig	293..323	CDD:431338	1/5 (20%)