Protein Alignment Antp and NKX2-6

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001129743.2
• Gene: NKX2-6 / 137814
• HGNCID: 32940
• Length: 301
• Species: Homo sapiens
• Alignment Length: 171
• Identity: 53/171 - (30%)
• Similarity: 78/171 - (45%)
• Gaps: 28/171 - (16%)

  Fly   216 PDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMM-----HQGQGPPQMHQGHP---GQHTPPSQNP 272
            |..:||| |....|..::..|..|.|.|.:.::     ..|:..|.::...|   |...|.....
Human    50 PRGSEVH-NAGGGGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVG 113

  Fly   273 NSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLT 337
            ||..|....      ||:..|.::|::.|..:::.|.|.||:.|...|||:...|..:|.||.||
Human   114 NSGDSVRGG------RSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLT 172

  Fly   338 ERQIKIWFQNRRMKWKKENKTK-----GEPGSGGEGDEITP 373
            ..|:||||||||.|.|::.:.|     |.|        :||
Human   173 STQVKIWFQNRRYKCKRQRQDKSLELAGHP--------LTP 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	23/97 (24%)
		Homeodomain	298..354	CDD:459649	25/55 (45%)
NKX2-6	NP_001129743.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..135		22/91 (24%)
		Homeodomain	133..189	CDD:459649	25/55 (45%)