Protein Alignment Antp and DBX1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001025036.2
• Gene: DBX1 / 120237
• HGNCID: 33185
• Length: 343
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 73/294 - (24%)
• Similarity: 102/294 - (34%)
• Gaps: 104/294 - (35%)

  Fly   173 MVPEGGSPPLV-------------DQMSGHHM---------------------NAQMTLPHHMGH 203
            :.|..|.|.|:             ...|||..                     .|.|: |...|.
Human     7 LAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPTASMS-PPRQGA 70

  Fly   204 PQA--QLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPP-----------QGMMHQG---Q 252
            |.|  ..|.:|:|.|            |...::.|.||....|           ..::..|   :
Human    71 PTALTDTGASDLGSP------------GPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGPRTE 123

  Fly   253 GPPQMHQGHP----------GQHTP---PSQNPNSQSSGMPSP-LYPWMRSQFGKCQERKRGRQT 303
            ..|.:.|..|          |...|   .|..|.| ||.:|.| .:.|..:..||.:.....|..
Human   124 TSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPAS-SSVVPIPGTFSWPLAARGKPRRGMLRRAV 187

  Fly   304 YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK--KENK--------- 357
            ::..|...|||.|...:|:::..|.::|..|.|.:.|:|||||||||||:  ||.:
Human   188 FSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCRE 252

  Fly   358 ----TK----------GEPGSGGEGDEITPPNSP 377
                ||          |:.|.|.|.:| ..|.||
Human   253 QTLPTKLNPHPDLSDVGQKGPGNEEEE-EGPGSP 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	39/196 (20%)
		Homeodomain	298..354	CDD:459649	23/57 (40%)
DBX1	NP_001025036.2	PRK12323	<49..182	CDD:481241	31/146 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..100		14/56 (25%)
		Homeodomain	184..238	CDD:459649	23/53 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..343		12/47 (26%)